Calculator: Breast cancer risk assessment by Gail Model (2018)

Appendix

Natural log relative risk factors (beta coefficients)

Variable	White	AfrnAmrcn	HispUSBorn	HispForgnBorn	NativAmrcn	AsianAmrcn
NBiop	0.529	0.182	0.097	0.480	0.529	0.553
AgeMen	0.094	0.267	0	0.259	0.094	0.075
Age1st	0.219	0	0.232	0.467	0.219	0.276
NRels	0.958	0.476	0.167	0.908	0.958	0.792
A50*NBiop	-0.288	-0.112	0	0	-0.288	0
Age1st*NRels	-0.191	0	0	0	-0.191	0

Attributable risk (AR50 coefficients)

Age	White	AfrnAmrcn	HispUSBorn	HispForgnBorn	NativAmrcn	AsianAmrcn
Age <50	0.579	0.729	0.749	0.429	0.579	0.475
Age ≥50	0.579	0.744	0.778	0.450	0.579	0.503

Breast cancer composite incidences (h1 coefficients)

AgeGrp	Ages	White	AfrnAmrcn	HispUSBorn	HispForgnBorn	NativAmrcn	Chinese	Japanese	Filipino	Hawaiian	OtrPacIsl	OtrAsian	WhiteAvg
1	20-24	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
2	25-29	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
3	30-34	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000	0.000
4	35-39	0.001	0.001	0.001	0.000	0.001	0.000	0.001	0.001	0.001	0.001	0.000	0.001
5	40-44	0.001	0.001	0.001	0.001	0.001	0.001	0.001	0.001	0.002	0.001	0.001	0.001
6	45-49	0.002	0.002	0.002	0.001	0.002	0.001	0.002	0.002	0.003	0.001	0.001	0.002
7	50-54	0.002	0.002	0.002	0.001	0.002	0.001	0.003	0.002	0.003	0.002	0.001	0.003
8	55-59	0.003	0.003	0.003	0.002	0.003	0.002	0.003	0.003	0.005	0.002	0.001	0.003
9	60-64	0.003	0.003	0.003	0.002	0.003	0.002	0.004	0.003	0.005	0.003	0.002	0.004
10	65-69	0.004	0.004	0.003	0.002	0.004	0.002	0.004	0.003	0.006	0.003	0.001	0.004
11	70-74	0.004	0.004	0.003	0.003	0.004	0.002	0.004	0.002	0.006	0.002	0.001	0.005
12	75-79	0.004	0.004	0.004	0.003	0.004	0.002	0.004	0.002	0.007	0.002	0.001	0.005
13	80-84	0.004	0.004	0.003	0.003	0.004	0.002	0.004	0.002	0.004	0.001	0.001	0.005
14	85-89	0.004	0.004	0.002	0.003	0.004	0.002	0.002	0.002	0.003	0.001	0.001	0.004

Competing mortality excluding breast cancer (h2 coefficients)

AgeGrp	Ages	White	AfrnAmrcn	HispUSBorn	HispForgnBorn	NativAmrcn	Chinese	Japanese	Filipino	Hawaiian	OtrPacIsl	OtrAsian	WhiteAvg
1	20-24	0.000	0.001	0.000	0.000	0.000	0.000	0.000	0.000	0.001	0.000	0.000	0.000
2	25-29	0.001	0.001	0.000	0.000	0.001	0.000	0.000	0.000	0.000	0.001	0.000	0.001
3	30-34	0.001	0.001	0.001	0.000	0.001	0.000	0.000	0.000	0.001	0.001	0.000	0.001
4	35-39	0.001	0.002	0.001	0.000	0.001	0.000	0.000	0.000	0.001	0.001	0.000	0.001
5	40-44	0.001	0.003	0.001	0.001	0.001	0.000	0.001	0.001	0.002	0.002	0.001	0.001
6	45-49	0.002	0.004	0.002	0.001	0.002	0.001	0.001	0.001	0.003	0.004	0.001	0.002
7	50-54	0.004	0.006	0.003	0.002	0.004	0.001	0.002	0.002	0.005	0.005	0.002	0.003
8	55-59	0.006	0.010	0.005	0.003	0.006	0.002	0.003	0.003	0.010	0.008	0.003	0.005
9	60-64	0.009	0.015	0.008	0.006	0.009	0.003	0.005	0.004	0.016	0.009	0.004	0.009
10	65-69	0.015	0.021	0.012	0.010	0.015	0.006	0.009	0.007	0.020	0.019	0.007	0.014
11	70-74	0.024	0.033	0.019	0.015	0.024	0.011	0.012	0.012	0.027	0.029	0.013	0.023
12	75-79	0.039	0.046	0.029	0.025	0.039	0.020	0.020	0.021	0.050	0.038	0.022	0.036
13	80-84	0.067	0.068	0.043	0.045	0.067	0.038	0.038	0.038	0.072	0.053	0.042	0.061
14	85-89	0.145	0.133	0.074	0.113	0.145	0.098	0.106	0.085	0.146	0.075	0.087	0.142

Age
Race/ethnicity/nativity (REN)
Number of prior breast biopsies (NBiop)	No biopsies (0)
	1 biopsy (1)
	2 or more biopsies (2)
	Unknown (0)
Biopsies with atypical hyperplasia (HyperPlasia)	No (-0.0725707)
	Yes (0.5988365)
	Unknown (0)
Age at menarche (AgeMen)	7 to 11 years old (2)
	12 to 13 years old (1)
	14 years or older (0)
	Unknown (0)
Age at first live birth (Age1st)	<20 years old (0)
	20 to 24 years old (1)
	25 to 29 years old (2)
	30 or more years old (3)
	Nulliparous (2)
	Unknown (0)
First-degree relatives with breast cancer (NRels)	None (0)
	1 relative (1)
	2 or more relatives (2)
	Unknown (0)


Relative risk when less than 50 years old
Relative risk when 50 or more years old

Average 5 year risk of breast cancer for a female of the same age and race/ethnicity in the general US population
Average lifetime risk of breast cancer for a female of the same age and race/ethnicity in the general US population

Patient 5 year risk of breast cancer
Patient lifetime risk of breast cancer

Decimal precision