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4
September 2025
This blood smear is from a patient who presented for a routine annual examination and was found to have mild macrocytic anemia. On the peripheral blood smear, some red blood cells (RBCs) showed pleomorphic ring-like forms with purple dots, resembling a parasitic infection by Babesia or Plasmodium species (refer to inset).
She reported a diagnosis of Hemoglobin Southampton (Casper) at 1 year of age and had undergone splenectomy. Hemoglobin Southhampton is a rare unstable hemoglobin variant that causes altered hemoglobin structure and hemolysis, with macrocytosis in some individuals. Other common features include hepatosplenomegaly and methemoglobinemia.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
