ART: antiretroviral therapy; HIV: human immunodeficiency virus; nPEP: nonoccupational post-exposure prophylaxis; TAF/FTC: tenofovir alafenamide-emtricitabine; TDF/FTC: tenofovir disoproxil fumarate-emtricitabine.
* Alternative regimens should be considered in certain settings. These include:¶ Discontinuing nPEP is reasonable in this setting since clinical trials have found that sexual transmission of HIV is unlikley if a persons with HIV is on ART and has a viral load <1000 copies/mL, particularly if the viral load is <200 copies/mL. However, some patients may still choose to continue nPEP after reviewing the risks and benefits. There are no data evaluating viral load thresholds for HIV transmission when the exposure was through IDU.
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