The severity of depression is determined by a combination of symptom number, frequency, severity, and duration and the degree of functional impairment. |
Severity |
Mild |
Individuals with mild major depression have ≥5 symptoms of depression and a PHQ-9 score of 5 to 9. They generally do not have: - Marked distress or significant functional impairment
- Frequent suicidal or homicidal ideation or plans
- Psychotic features (eg, delusions or hallucinations)
- Catatonic features (eg, immobility, mutism, excessive purposeless motor activity)
- Significant aggressiveness
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Moderate |
Individuals with moderate major depression have ≥5 symptoms of depression and a PHQ-9 score of 10 to 19. They may have suicidal or homicidal ideation and plans. They generally do not have: - Psychotic features (eg, delusions or hallucinations)
- Catatonic features (eg, immobility, mutism, excessive purposeless motor activity)
- Marked distress or functional impairment
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Severe |
Individuals with severe major depression have ≥7 symptoms of depression or a PHQ-9 score of ≥20 or any of the following: - Psychotic features (eg, delusions or hallucinations)
- Catatonic features (eg, immobility, mutism, excessive purposeless motor activity)
- Marked distress or functional impairment
- Very likely to have suicidal or homicidal ideation and behavior (ie, a specific plan and intent to act upon it)
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Symptoms of major depression |
An episode of major depression consists of a period of at least 2 consecutive weeks with 5 or more of the following symptoms. Symptoms must be present nearly every day, and at least 1 of the symptoms must be depressed mood or anhedonia: - Depressed mood
- Anhedonia (decreased interest or pleasure in activities previously considered enjoyable)
- Unintended change in appetite or weight
- Insomnia or hypersomnia
- Psychomotor agitation or significant slowing
- Decreased energy or fatigue
- Feelings of worthlessness or excessive guilt
- Poor concentration or new indecisiveness
- Recurrent thoughts about death or suicide
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