Drug or drug class | Side effects |
Antihistamines | Sedation, dry mouth, lightheadedness, and constipation |
Dopamine antagonists | Anticholinergic effects (dry mouth, sedation) and dystonia |
| Anxiety, depression, restlessness, hyperprolactinemia, QT prolongation, and irreversible tardive dyskinesia with high doses and long-term use |
| Drowsiness, dizziness, headaches, urinary retention, and, rarely, extrapyramidal symptoms and QT prolongation |
| Maternal sedation, risk of dystonic reactions with prolonged use and at higher doses, and may lower the seizure threshold, which should be considered in patients with seizure disorder |
Ondansetron | Headache, fatigue, constipation, and drowsiness |