LDL-C lowering for secondary prevention of ASCVD: Management based upon response to therapy

This algorithm is a guide to management of LDL-C in patients with known ASCVD without recent acute coronary syndrome and without familial hypercholesterolemia. This algorithm focuses on management based upon LDL-C response to 4 to 6 weeks of an initial drug regimen. Refer to UpToDate content on LDL-C lowering after an acute coronary syndrome or with familial hypercholesterolemia. ASCVD includes atherosclerotic coronary artery disease (>50% stenosis, angina, or MI), cerebrovascular disease (stroke or transient ischemic attack), peripheral vascular disease, and disease of the aorta.