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The nonconvulsive status epilepticus response scale for measurement of clinical improvement in response to intravenous antiseizure medication

The nonconvulsive status epilepticus response scale for measurement of clinical improvement in response to intravenous antiseizure medication
Level 10: Normal
Level 9: Speaks or writes words with clear sense, oriented to person, year, and city or region, but behavior or performance different than normal
Level 8: Speaks or writes words with clear sense, but disoriented to person, year, and city or region
Level 7: Speaks or writes words or syllables, incomprehensible or confused
Level 6: Follows commands (verbally or by demonstration) (eg, open/close eyes, raise arms, say "1, 2, 3")
Level 5: Directed gaze to examiner (or responsive vertical eye movement in locked-in syndrome), does not follow any commands (neither verbal nor by demonstration)
Level 4: Opens eyes spontaneously or to verbal stimulus or to light touch (no directed gaze), does not follow any commands
Level 3: Opens eyes to (strong) tactile stimulus (right or left shoulder, nose), does not follow commands (neither verbal nor by demonstration)
Level 2: Localizes to/wards off painful stimuli
Level 1: No purposeful response to painful stimuli
For scoring, use the highest level achieved before and after medication. At least one-step improvement on the NRS or a definite time-locked improvement in a focal deficit poses a positive response to treatment.
NRS: nonconvulsive status epilepticus response scale.
From: Leitinger M, Gaspard N, Hirsch LJ, et al. Diagnosing nonconvulsive status epilepticus: Defining electroencephalographic and clinical response to diagnostic intravenous antiseizure medication trials. Epilepsia 2023; 64:2351. https://onlinelibrary.wiley.com/doi/10.1111/epi.17694. Copyright © 2023 The Authors. Epilepsia published by Wiley Periodicals LLC on behalf of International League Against Epilepsy. This image has been provided by or is owned by Wiley. Further permission is needed before it can be downloaded to PowerPoint, printed, shared or emailed. Please contact Wiley's permissions department either via email: [email protected] or use the RightsLink service by clicking on the 'Request Permission' link accompanying this article on Wiley Online Library (https://onlinelibrary.wiley.com/).
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