Prevalence of skeletal and biochemical abnormalities in different stages of pediatric chronic kidney disease
Prevalence of abnormalities related to CKD-MBD, based on studies in 52 patients 2 to 21 years of age with predialysis CKD. The mineralization defect was defined as an abnormal accumulation of osteoid (osteoid volume) in combination with a delayed osteoid maturation time. Increased PTH and FGF23 values were defined as those above the range determined in healthy individuals.
Reproduced with permission from Wolter Kluwer Health, Inc.: Wesseling-Perry K, Pereira RC, Tseng CH, et al. Early skeletal and biochemical alterations in pediatric chronic kidney disease. Clin J Am Soc Nephrol 2011; 7(1):146-152. Copyright © The Authors.
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