MRI of a child nine years of age with chronic epilepsy. Transverse-axial (A, B) and coronal (C) T2-weighted MRIs show gray matter-intensity band (b) of moderate thickness separated from cortex with shallow sulci by a layer of partially myelinated white matter (w). This is a distinctive type of microtubule-associated protein malformation since only approximately half of the neurons are affected. The severity of the clinical syndrome is associated with the thickness of the band: A thicker band is associated with a more severe neurologic outcome.
