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Nonspinal etiologies of low back pain in adults

Nonspinal etiologies of low back pain in adults
  Key features on history or physical examination Initial imaging Additional initial studies
Musculoskeletal conditions
Hip pathology

Primary hip pathology may refer pain to the lower back

Pain is exacerbated by internal or external rotation of the hip

Hip range of motion may be reduced

Hip radiographs to exclude fracture, in moderate to severe chronic hip pain, or as initial assessment of hip osteoarthritis None
Piriformis syndrome

Gradual-onset buttock pain that increases with sitting

Symptoms may mimic sciatica

None None
Sacroiliac joint dysfunction Pelvic pain or back pain with provocative tests of the sacroiliac region* None None
Psychologic conditions History of depression or somatization, or recent traumatic event None None
Herpes zoster Dermatomal allodynia followed by an erythematous, vesicular rash None Laboratory testing for VZV if the clinical presentation is uncertain
Lower extremity peripheral artery disease

Commonly associated with a history of smoking, hypertension, diabetes, and other cardiovascular risk factors

Pain is primarily in the lower extremities, typically worse with activity and relieved with rest

If severe, patients may have pain at rest and associated skin discoloration, nonhealing wounds, or ulceration

None Resting ABI
Intra-abdominal pathologies

Pancreatitis, nephrolithiasis, pyelonephritis, abdominal aortic aneurysm, and other abdominal pathologies may present with low back pain

Other suggestive, accompanying symptoms are typically present

Please refer to related UpToDate content for further information on each condition

CT or MRI based on the condition suggested by accompanying symptoms  
This table summarizes common nonspinal conditions that may refer pain to the lower back. While nonspecific low back pain is the most common etiology of low back pain, it is a presumptive diagnosis after no features suggestive of other etiologies are found on evaluation. Please review related UpToDate content for further details on each condition.

ABI: ankle-brachial systolic pressure index; CT: computed tomography; MRI: magnetic resonance imaging; VZV: varicella-zoster virus.

* Refer to related UpToDate content for further details regarding examination of the sacroiliac joint, hip, and groin.

Graphic 148504 Version 1.0

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