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Patient education: Testicular cancer (The Basics)

Patient education: Testicular cancer (The Basics)

What is testicular cancer? — Testicular cancer happens when normal cells in 1 or both testicles change into abnormal cells and grow out of control. The testicles are found inside a skin sac called the "scrotum" (figure 1). They make sperm and male hormones.

Testicular cancer occurs most often between the ages of 15 and 35. There are different types of testicular cancer. But most cases of testicular cancer, whatever the type, can be cured with treatment.

What are the symptoms of testicular cancer? — The first symptom of testicular cancer is often a lump or swelling in the scrotum that is not painful. Other symptoms can include:

A dull ache or heavy feeling in the low belly, or around the anus or scrotum

Pain in the testicles or scrotum

These symptoms can be caused by conditions that are not cancer. But if you feel a lump in your testicle, see your doctor or nurse as soon as possible.

Is there a test for testicular cancer? — Yes. If your doctor or nurse thinks that you might have testicular cancer, they might order a testicular ultrasound. This is an imaging test that creates pictures of the inside of the testicles and can show abnormal growths. A mass or lump seen on ultrasound can be a sign of testicular cancer.

The only way to know for sure if you have testicular cancer is for a doctor to remove the abnormal testicle and send it to a lab to be checked for cancer. Surgery to remove a testicle is called an "orchiectomy."

What is cancer staging? — Cancer staging is a way for doctors to find out if the cancer has spread beyond the testicles to other parts of the body. Staging usually involves blood tests, CT scans, or other imaging tests. Based on the test results, the cancer is then given a "stage," for example, "stage 1." The stage of your cancer helps your doctor to figure out your options for treatment.

How is testicular cancer treated? — Removing the testicle is the first part of treatment. Further treatment depends on:

The type of cancer that is found

Whether there is a risk that the cancer could return – This risk is based on the type of cancer, but also on whether it has spread outside of the testicle. In some cases, doctors will also do blood tests to check "tumor markers." These are substances in the blood produced by the cancer. Measuring the levels of these markers can help guide treatment.

In general, the treatment options for testicular cancer could include any of the following:

Chemotherapy – Chemotherapy is the medical term for medicines that kill cancer cells or stop them from growing.

Radiation therapy – Radiation kills cancer cells.

Surgery – Testicular cancer is sometimes treated with surgery to remove nearby lymph nodes, which are bean-shaped internal organs. This surgery can help prevent the spread of testicular cancer in the body. A doctor might also do surgery to remove a mass in another part of the body if the cancer has spread.

Monitoring for changes – If you have early testicular cancer, treatment beyond removing the testicle is not always needed. In these cases, doctors sometimes recommend simply monitoring the body for changes that could indicate the return of cancer. This involves getting regular exams, blood tests, and imaging tests. It is also called "surveillance."

What if I want to have a child one day? — If you want to be able to get a partner pregnant in the future, talk with your doctor. Some treatments for testicular cancer can reduce or stop sperm production. You might choose to store your sperm before treatment so you can use it in the future to have a child.

What happens after treatment? — After treatment, you will be checked every so often to see if the cancer comes back. Follow-up tests usually include exams, blood tests, and imaging tests.

What happens if the cancer comes back or spreads? — If the cancer comes back or spreads, you might have more chemotherapy, radiation therapy, or surgery.

What else should I do? — Follow all your doctors' instructions about visits and tests. It's also important to talk to your doctor about any side effects or problems you have during treatment.

Getting treated for testicular cancer involves making many choices, such as what treatment to have.

Always let your doctors and nurses know how you feel about a treatment. Any time you are offered a treatment, ask:

What are the benefits of this treatment? Is it likely to help me live longer? Will it reduce or prevent symptoms?

What are the downsides to this treatment?

Are there other options besides this treatment?

What happens if I do not have this treatment?

More on this topic

Patient education: What are clinical trials? (The Basics)
Patient education: Preserving fertility after cancer treatment in men (The Basics)

Patient education: Testicular cancer (Beyond the Basics)
Patient education: Treatment of male infertility (Beyond the Basics)
Patient education: Evaluation of infertility in couples (Beyond the Basics)

This topic retrieved from UpToDate on: Feb 02, 2024.
Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider's examination and assessment of a patient's specific and unique circumstances. Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient. UpToDate, Inc. and its affiliates disclaim any warranty or liability relating to this information or the use thereof. The use of this information is governed by the Terms of Use, available at https://www.wolterskluwer.com/en/know/clinical-effectiveness-terms. 2024© UpToDate, Inc. and its affiliates and/or licensors. All rights reserved.
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