Version June 2024
| Dextrose | Amino acid | Icodextrin | ||
| Low Ca++ | High Ca++ | |||
| Osmolality (mOsm/kg) | 346, 396, and 485 | 346, 396, and 485 | 365 | 282 |
| Molecular weight (Dalton) | 182 | 182 | 100 to 200 | 20,000 |
| Advantages | Well studied Most commonly used for a long time Side-effect profile well known to most of the nephrologists Allow the use of oral calcium-containing phosphate binders | Same as low-calcium solutions except it may help bringing up serum calcium in patients with low calcium levels | Can improve nutritional status in malnourished diabetic and/or patients with recurrent peritonitis | Sustained ultrafiltration for many hours Decreased solute absorption |
| Disadvantages | Short-lived ultrafiltration Metabolic complications like hyperinsulinemia, hyperglycemia, hyperlipidemia, and weight gain Can lead to low serum calcium and bone disease | Same as low calcium except it can limit the use of calcium-containing oral phosphate binders | Expensive May increase nitrogen waste product in blood May cause/worsen acidosis | Increases serum levels of maltose, maltotriose, and oligopolysacharides |
| Indications | Commonly used, first-line PD solution in all patients unless special circumstances exist High serum phosphorus and normal to high serum calcium | Used in patients who have low calcium levels with low calcium-containing dialysis solutions | Malnourished diabetic patients or Malnourished patients with recurrent peritonitis | Patients who lose ultrafiltration In patients with automated PD situation during the dry day to achieve sustained UF and increased solute and fluid removal In diabetic patients |
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