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خرید پکیج

تعداد آیتم قابل مشاهده باقیمانده : -9 مورد

Possible biologic mechanisms for exercise-induced reductions in all-cause and cardiac mortality

Possible biologic mechanisms for exercise-induced reductions in all-cause and cardiac mortality

Metabolic effects	Enhanced insulin sensitivity and insulin-independent glucose uptake Improved lipid profile Improved HDL cholesterol efflux capacity Improved HDL cholesterol antioxidative capacity Reduced weight gain
Anti-inflammatory effects	Decreased inflammatory markers Reduced oxidative tissue damage Promotion of antioxidant defenses
Hemostatic factors	Reduced platelet adhesion and aggregation Enhanced fibrinolytic activity Improved blood viscosity
Cardiovascular effects	Increased myocardial contractility Improved LV remodeling Increased peripheral venous tone Reduced resting and exercise blood pressure Reduced resting and exercise heart rate Reduced myocardial oxygen demand (submaximal physical activity levels) Plasma volume expansion Enhanced parasympathetic tone Increased endothelium-dependent vasodilation Improved endothelial cell integrity Atherosclerotic plaque stabilization Increased gene expression for nitric oxide synthase Reduced carotid intima-media thickness Reduced coronary artery thickness Increased coronary artery dilation and blood flow Increased coronary collateral vessels
Lifestyle factors	Decreased likelihood of smoking Short-term reduction in appetite Improvement in symptoms of depression and anxiety Possible stress reduction

HDL: high-density lipoprotein; LV: left ventricular.

References:

Shephard RJ, Balady GJ. Exercise as cardiovascular therapy. Circulation 1999; 99:963.
Valenzuela PL, Ruilope LM, Santos-Lozano A, et al. Exercise benefits in cardiovascular diseases: From mechanisms to clinical implementation. Eur Heart J 2023; 44:1874.

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