Version June 2024
| Site of lesion | Associated tumors | Clinical findings |
| Anterior parts | Carcinoma invasive from frontal and ethmoid sinuses; meningiomas | Unilateral anosmia, frontal lobe syndrome, seizures |
| Superior orbital fissure | Meningiomas, carcinoma of nasopharynx | III, IV, V, VI cranial nerve lesions with ophthalmoplegia; pain and hypesthesia in distribution of V |
| Cavernous sinus | Chordomas, meningiomas, sellar, and parasellar tumors | III, IV, VI, and sometimes V nerve involvement with ophthalmoplegia |
| Apex of the petrous temporal bone | Cholesteatoma, chordoma, meningioma, neurinoma, sarcoma | V and VI nerve involvement with sensory and motor findings and diplopia |
| Sphenoid and petrous bone | Meningioma, chordoma, nasopharyngeal carcinoma, metastasis | III, IV, VI nerve lesions result in ophthalmoplegia; V may be associated with trigeminal neuralgia syndrome |
| Jugular foramen | Glomus jugulare tumors, neurinomas, chordomas, cholesteatoma, meningiomas, nasopharyngeal carcinoma | IX, X, XI nerves producing difficulty with swallowing, speaking, and weakness of strap muscles of neck |
| Cerebellopontine angle | Neurinoma, meningioma, cholesteatoma, metastasis cerebellar tumors | VIII nerve lesions causing loss of hearing, vertigo, and nystagmus; cerebellar lesions producing ataxia of limbs and gait; V, VII, and occasionally IX and XII nerve lesions; brainstem symptoms and signs of increased intracranial pressure |
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