Version May 2024
| Pancrelipase preparations (United States trade name) | Description and United States manufacturer (refer to NOTE) | Administration | Lipase (USP units) | Amylase (USP units) | Protease (USP units) |
| Pancreaze 2600 | Delayed-release capsule containing enteric-coated microtablets, porcine origin. (VIVUS, Inc) | Applies to Pancreaze, Creon, Zenpep: Preparation is suitable for use in adults, children, and infants. Swallow capsules whole or sprinkle capsule contents on small amount of acidic, soft food with pH of 4.5 or less (eg, applesauce, yogurt, commercially prepared bananas or pears). Consume immediately and follow with water, juice, or other liquid. Do not crush or chew capsule shell or contents. For infants, contents of the capsule may also be administered directly into the mouth, followed by breast milk or formula*. | 2600 | 15,200 | 8800 |
| Pancreaze 4200 | 4200 | 24,600 | 14,200 | ||
| Pancreaze 10,500 | 10,500 | 61,500 | 35,500 | ||
| Pancreaze 16,800 | 16,800 | 98,400 | 56,800 | ||
| Pancreaze 21,000 | 21,000 | 83,900 | 54,700 | ||
| Pancreaze 37,000 | 37,000 | 149,000 | 97,300 | ||
| Creon 3 | Delayed-release capsule containing enteric-coated minimicrospheres, porcine origin. (AbbVie, Inc) | 3000 | 15,000 | 9500 | |
| Creon 6 | 6000 | 30,000 | 19,000 | ||
| Creon 12 | 12,000 | 60,000 | 38,000 | ||
| Creon 24 | 24,000 | 120,000 | 76,000 | ||
| Creon 36 | 36,000 | 180,000 | 114,00 | ||
| Zenpep 3 | Delayed-release capsule containing enteric-coated beads, porcine origin. (Aimmune Therapeutics, Inc) | 3000 | 14,000 | 10,000 | |
| Zenpep 5 | 5000 | 24,000 | 17,000 | ||
| Zenpep 10 | 10,000 | 42,000 | 32,000 | ||
| Zenpep 15 | 15,000 | 63,000 | 47,000 | ||
| Zenpep 20 | 20,000 | 84,000 | 63,000 | ||
| Zenpep 25 | 25,000 | 105,000 | 79,000 | ||
| Zenpep 40 | 40,000 | 168,000 | 126,000 | ||
| Viokace 10,440 | Regular-release (non-enteric-coated) tablet, porcine origin. (Nestlé Healthcare Nutrition, Inc) | Only indicated for use in adult patients also treated with a proton pump inhibitor. Swallow tablets whole with sufficient liquid. Do not crush or chew. Preparation is not suited for infants or children who do not readily swallow whole pills. | 10,440 | 39,150 | 39,150 |
| Viokace 20,880 | 20,880 | 78,300 | 78,300 | ||
| Pertzye 4 | Delayed-release capsule containing bicarbonate-buffered, enteric-coated microspheres, porcine origin. (Digestive Care, Inc) | Preparation is suitable for use in adults, children, and infants. Swallow capsules whole or sprinkle capsule contents on small amount of acidic, soft food with pH of 4.5 or less (eg, applesauce, yogurt, commercially prepared bananas or pears). Consume immediately and follow with water, juice, formula, or breast milk as appropriate. Do not crush or chew capsule shell or contents. Do not mix contents of capsule in formula or breast milk. Pertzye 24 is indicated for children over 12 months of age and adults. | 4000 | 15,125 | 14,375 |
| Pertzye 8 | 8000 | 30,250 | 28,750 | ||
| Pertzye 16 | 16,000 | 60,500 | 57,500 | ||
| Pertzye 24 | 24,000 | 90,750 | 86,250 |
This table shows USP units of enzyme activity for product brands available in the United States. Individual product contents, preparation type, and units of activity vary by country. The units of activity used in other countries are not equivalent to the USP units shown in this table (unless the data are specifically given as USP units). Consult local prescribing information before use or changing products.
NOTE: Products are not equivalent to one another and are not automatically interchangeable with any other pancreatic enzyme replacement product.USP: United States Pharmacopeial.
* Care should be taken to be sure that the capsule contents (pellets) are not crushed or retained in the mouth, to avoid irritation of the oral mucosa. Do not mix directly into infant formula or breast milk, as this may diminish efficacy.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
