Frequency and severity of laboratory findings among imitators of preeclampsia

Laboratory findings	HELLP syndrome	AFLP	TTP	HUS	Exacerbation of SLE
Thrombocytopenia (less than 100,000/mm³)	More than 20,000	More than 50,000	20,000 or less	More than 20,000	More than 50,000
Hemolysis (%)	50 to 100	15 to 20	100	100	14 to 23 in patients with APA
Anemia (%)	Less than 50	Absent	100	100	14 to 23 in patients with APA
DIC (%)	Less than 20	50 to 100	Rare	Rare	Rare
Hypoglycemia (%)	Absent	50 to 100	Absent	Absent	Absent
VW factor multimers (%)	Absent	Absent	80 to 90	80	Less than 10
ADAMTS13 less than 5% (%)	Absent	Absent	33 to 100	Rare	Rare
Impaired renal function (%)	50	90 to 100	30	100	40 to 80
LDH (international units/L)	600 or more	Variable	More than 1000	More than 1000	May be elevated in patients with APA and liver involvement
Elevated ammonia (%)	Rare	50	Absent	Absent	Absent
Elevated bilirubin (%)	50 to 60	100	100	NA	Less than 10
Elevated transaminases (%)	100	100	Usually mild*	Usually mild*	In patients with APA and liver involvement

HELLP: hemolysis, elevated liver enzymes, low platelets; AFLP: acute fatty liver of pregnancy; TTP: thrombotic thrombocytopenic purpura; HUS: hemolytic uremic syndrome; SLE: systemic lupus erythematosus; APA: antiphospholipid antibodies with or without catastrophic antiphospholipid syndrome; DIC: disseminated intravascular coagulopathy; VW: von Willebrand; ADAMTS13: von Willebrand factor-cleaving metalloprotease; LDH: lactic dehydrogenase; NR: values not reported.
* Levels less than 100 international units/L.

Graphic 65674 Version 13.0

خرید پکیج

Frequency and severity of laboratory findings among imitators of preeclampsia