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خرید پکیج
تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
نسخه الکترونیک
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Nonpharmacologic interventions for refractory gastroparesis

Nonpharmacologic interventions for refractory gastroparesis
Intervention Available procedures Purpose Advantages Disadvantages
Nasogastric tube

Blind

Radiologic (under fluoroscopy)

Decompression

Access for feeding or medications

Ease of placement

Simple procedure

Low cost

Easily displaced/removed

Short-term use only

Discomfort

Source of infection

Risk of tube blockage

Potentially increased reflux, aspiration of feeds
Gastrostomy tube

Surgical

Radiologic

Percutaneous endoscopic

Decompression

Feeding

Superior for decompression

Moderate ease of placement

Bolus feeding may occasionally be possible by gastrostomy tube alone

Potentially long term

Questionable value for nutritional support without jejunal tube placement

Source of infection

Risk of tube blockage

High risk of reflux, aspiration of feeds
Jejunostomy tube (direct)

Surgical

Radiologic

Percutaneous endoscopic
Feeding

Superior for nutritional purposes

Potential for long-term use

Source of infection

Risk of tube blockage

Requires enteral infusion pump for nutrition

Does not provide for gastric decompression
Jejunostomy tube (trans-gastric)

Radiologic

Percutaneous endoscopic
Biluminal enteral tube with separate gastric and jejunal ports

Single tube

Single procedure for two tubes

Single stoma/abdominal

Can accomplish decompression and feedings through different ports of the same tube

Risk of migration of jejunal tube into stomach

Reflux of feeds into stomach

Source of infection

Risk of tube blockage (especially jejunal port)

Technically somewhat more difficult to place the jejunal tube
Separate gastrostomy and jejunostomy tubes

Radiologic

Percutaneous endoscopic

Decompression

Feeding

Two separate simultaneously working tubes

Decreased risk of reflux, aspiration of feeds

Provides gastric decompression

Longer, more difficult procedure

Higher cost due to two procedures

Higher risk of infection due to two stomas/wounds

Risk of tube blockage
Gastrojejunostomy with or without percutaneous jejunostomy (open versus laparoscopic) Surgical Surgical bypass for decompression and feeding

Drainage by gravity

Potentially permanent

Most useful in gastric outlet obstruction syndrome

Increased morbidity of surgery

Needs careful patient selection

Gastroparesis, if significant, may not be alleviated and may require jejunal tube placement regardless

Higher cost of procedure

High expertise required for the procedure
Gastric electrical stimulation Surgical

Feeding

Enteral passage of secretions

Physiologic

Potentially eliminates the need for enteral feeding

No foreign body on body surface (tubes)

Decreased risk of infection

More expertise required

Cost of procedure and device

Unknown benefit for MG (currently, gastric electric stimulation is not used in MG and is still controversial in gastroparesis. Patients are required to have a life expectancy of >6 years).
MG: malignant gastroparesis.
Reproduced with permission from: Donthireddy K, Ailawadhi S, Nasser E, et al. Malignant gastroparesis: pathogenesis and management of an underrecognized disorder. J Support Oncol 2007; 5:355. Illustrations used with the permission of Elsevier Inc. All rights reserved.
Graphic 76547 Version 5.0

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