Treatment of Cushing disease

MRI: magnetic resonance imaging.

* The choice of treatment after failed transsphenoidal surgery should be individualized for each patient based upon the presence of dural or cavernous sinus invasion, the presence of a surgical target on MRI, the location of tumor in relationship to optic nerves, the need for prompt resolution of hypercortisolism, contraindication to specific medical therapy, and the patient's values and preferences.