Hyperthyroidism due to increased thyroid hormone synthesis |
Autoimmune thyroid disease |
Graves' disease |
Hashitoxicosis* |
Autonomous thyroid tissue¶ |
Toxic adenoma |
Toxic multinodular goiter |
TSH-mediated hyperthyroidism |
TSH-producing pituitary adenoma |
Non-neoplastic TSH-mediated hyperthyroidism |
Human chorionic gonadotropin-mediated hyperthyroidism |
Hyperemesis gravidarum |
Trophoblastic disease (choriocarcinoma, molar pregnancy) |
Hyperthyroidism due to release of preformed thyroid hormone |
Thyroiditis |
Subacute granulomatous (de Quervain's) thyroiditis |
Painless thyroiditis (silent thyroiditis, lymphocytic thyroiditis) |
Postpartum thyroiditis |
Amiodarone (also may cause iodine-induced hyperthyroidism) |
Checkpoint inhibitor-induced thyroiditis |
Radiation thyroiditis |
Palpation thyroiditis |
Hyperthyroidism due to exogenous thyroid hormone intake |
Excessive replacement therapy |
Intentional suppressive therapy |
Factitious hyperthyroidism |
Ectopic hyperthyroidism |
Struma ovarii (ectopic thyroid tissue in an ovarian teratoma) |
Metastatic follicular thyroid cancer |
TSH: thyroid-stimulating hormone.
* Hashitoxicosis is a variant of Hashimoto's thyroiditis that presents with high thyrotropin receptor antibodies and hyperthyroidism (high radioiodine uptake) with transition to overt hypothyroidism over 3 to 12 months.
¶ Radioiodine uptake may be low if recent iodine load led to iodine-induced hyperthyroidism.