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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Microbiology of preseptal and orbital cellulitis*

Microbiology of preseptal and orbital cellulitis*
  Preseptal cellulitis Orbital cellulitis
Chaudhry, et al[1] Botting, et al[2] McKinley, et al[3] Seltz, et al[4] Nageswaran, et al[5] Botting, et al[2] Goytia, et al[6]
Number of patients 104 227 38 94 41 35 85
Number of patients with a positive culture (except) 36 53 24 29 20 11 29
Staphylococcus aureus Δ 32 11 8 3 7 14
MSSA NR NR 3 7 NR NR 7
MRSA NR NR 8 1 NR NR 7
Alpha-hemolytic streptococci (including S. pneumoniae) or non-hemolytic streptococci Δ     4 7   15
Beta-hemolytic streptococci (including S. pyogenes) Δ 7 13 6 5 3 10
Streptococcus anginosus (formerly S. milleri)   2   14   2  
Rothia mucilaginosa             1
Haemophilus influenzae 8 5 3 3 3   5
Haemophilus parainfluenzae             1
Klebsiella pneumoniae 3           1
Moraxella catarrhalis         1    
Arcanobacterium spp       1 1    
Eikenella corrodens       1 2    
Anaerobes   2   2 8   4
Skin flora/contaminant   5 11◊ 12◊      
Possible pathogen§       10      
Sites of culture Blood, wound, abscess NR Blood, orbital abscess, eye, sinus, epidural abscess, nose Blood, sinus/orbit, subdural space Orbital abscess, subperiostial abscess, sinus NR Blood, endoscopic sinus, subperiosteal, intraorbital
MSSA: methicillin-susceptible Staphylococcus aureus; MRSA: methicillin-resistant Staphylococcus aureus; NR: not reported.
* Results are reported as the number of cultures that grew a given organism. Some cultures grew >1 organism and some patients had >1 positive culture.
¶ Results are reported as number of positive cultures (rather than number of patients with a positive culture); some patients may have had >1 positive culture.
Δ Staphylococcus spp and Streptococcus spp were recovered from 26 (72 percent) of cultures, but the authors did not report the number of positive cultures for individual species.
◊ In McKinley, et al[3], coagulase-negative Staphylococcus spp was reported as a recovered organism, but in Seltz, et al[4], this organism was classified as a contaminant. We have classified it as a contaminant for both studies.
§ The authors of this study classifed some (but not all) sinus/orbit cultures as possible pathogens rather than true pathogens.
References:
  1. Chaudhry IA, Shamsi FA, Elzaridi E, et al. Inpatient preseptal cellulitis: experience from a tertiary eye care centre. Br J Ophthalmol 2008; 92:1337.
  2. Botting AM, McIntosh D, Mahadevan M. Paediatric pre- and post-septal peri-orbital infections are different diseases. A retrospective review of 262 cases. Int J Pediatr Otorhinolaryngol 2008; 72:377.
  3. McKinley SH, Yen MT, Miller AM, Yen KG. Microbiology of pediatric orbital cellulitis. Am J Ophthalmol 2007; 144:497.
  4. Seltz LB, Smith J, Durairaj VD, et al. Microbiology and antibiotic management of orbital cellulitis. Pediatrics 2011; 127:e566.
  5. Nageswaran S, Woods CR, Benjamin DK Jr, et al. Orbital cellulitis in children. Pediatr Infect Dis J 2006; 25:695.
  6. Goytia VK, Giannoni CM, Edwards MS. Intraorbital and intracranial extension of sinusitis: comparative morbidity. J Pediatr 2011; 158:486.
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