Induration 5 mm or greater |
Children in close contact with known or suspected contagious people with tuberculosis disease |
Children suspected to have tuberculosis disease:
|
Children receiving immunosuppressive therapyΔ or with immunosuppressive conditions, including human immunodeficiency (HIV) infection |
Induration 10 mm or greater |
Children at increased risk of disseminated tuberculosis disease:
|
Children with likelihood of increased exposure to tuberculosis disease:
|
Induration 15 mm or greater |
Children age four years or older without any risk factors |
* These definitions apply regardless of previous Bacille Calmette-Guérin immunization; erythema alone at TST site does not indicate a positive test result. Tests should be read at 48 to 72 hours after placement.
¶ Evidence by physical examination or laboratory assessment that would include tuberculosis in the working differential diagnosis (eg, meningitis).
Δ Including immunosuppressive doses of corticosteroids or tumor necrosis factor-alpha antagonists or blockers, or drugs used in transplant recipients.
◊ Some experts define significant travel as travel or residence in a high-prevalence region for at least one month.