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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Histologic findings in patients with idiopathic noncirrhotic portal hypertension

Histologic findings in patients with idiopathic noncirrhotic portal hypertension
Histologic feature* Frequency (percent)
Irregular intimal thickening of portal veins 75-100
Organizing thrombus and/or recanalization of portal veins 20-100
Intralobular fibrous septa 95
Abnormal blood vessels in the lobules 75
Subcapsular atrophy 70
Dense portal fibrosis and portal venous obliteration 32-52
Periductal fibrosis of interlobular bile ducts 50
Portal inflammation 47
Nodular hyperplasia of parenchyma 25-40
* Needle biopsies from patients with idiopathic noncirrhotic portal hypertension are typically normal or show only nonspecific morphologic changes. Specific abnormalities are more commonly seen in larger wedge biopsies or autopsy specimens.
¶ Studies showing findings in 100 percent of patients were based upon autopsy specimens.
Data from:
  1. Sarin SK, Kapoor D. Non-cirrhotic portal fibrosis: current concepts and management. J Gastroenterol Hepatol 2002; 17:526.
  2. Hillaire S, Bonte E, Denninger MH, et al. Idiopathic non-cirrhotic intrahepatic portal hypertension in the West: a re-evaluation in 28 patients. Gut 2002; 51:275.
  3. Ludwig J, Hashimoto E, Obata H, Baldus WP. Idiopathic portal hypertension; a histopathological study of 26 Japanese cases. Histopathology 1993; 22:227.
  4. Nakanuma Y, Hoso M, Sasaki M, et al. Histopathology of the liver in non-cirrhotic portal hypertension of unknown aetiology. Histopathology 1996; 28:195.
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