Histopathology of lymphomatoid papulosis

(A) Early perivascular lesion.
(B) Neutrophils within and around blood vessels are characteristic.
(C) Mature wedge-shaped lesion.
(D) Advanced ulcerated lesion.
Early lesions have a perivascular lymphoid infiltrate. Mature lesions have a wedge-shaped appearance. The most common type A lesions have large Reed-Sternberg-like cells and frequent mitoses in an inflammatory background. Type B lesions resemble mycosis fungoides (MF) and may be a papular variant of MF. Type C lesions demonstrate a relatively monotonous population of large CD30+ cells with few inflammatory cells.