(A) This graph shows the effects of various antihypertensive therapies on afferent and efferent arteriolar tone in unilaterally nephrectonized diabetic hypertensive dogs.
(B) This graph shows the effects of an ace inhibitor or calcium blocker on mesangial matrix proliferation in diabetic dogs.
(A) Adapted by permission from Macmillan Publishers Ltd: Kidney International. Brown SA, Walton CL, Crawford P, Bakris GL. Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria. Kidney Int 1993; 43:1210.
http://www.nature.com/ki/index.html. Copyright © 1993.
(B) Adapted by permission from Macmillan Publishers Ltd: Kidney International. Gaber L, Walton C, Brown S, Bakris G. Effects of different antihypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs. Kidney Int 1994; 46:161.
http://www.nature.com/ki/index.html. Copyright © 1994.
