Proposed diagnostic criteria for polycystic ovary syndrome

NIH consensus criteria 1990^[1] (all required)	Rotterdam criteria 2003*^[2] (two out of three required)	AES definition 2008^[3] (all required)
Menstrual irregularity due to oligo- or anovulation	Oligo- or anovulation	Clinical and/or biochemical signs of hyperandrogenism
Clinical and/or biochemical signs of hyperandrogenism	Clinical and/or biochemical signs of hyperandrogenism	Ovarian dysfunction – oligo/anovulation and/or polycystic ovaries on ultrasound
Exclusion of other disorders: NCCAH, androgen-secreting tumors	Polycystic ovaries (by ultrasound)	Exclusion of other androgen excess or ovulatory disorders

NIH: National Institutes of Health; AES: Androgen Excess Society; NCCAH: nonclassic congenital adrenal hyperplasia; PCOS: polycystic ovary syndrome.
* Rotterdam criteria also require exclusion of other conditions that mimic PCOS. Criteria were developed at a 2003 consensus meeting held in Rotterdam (European Society of Human Reproduction and Embryology [ESHRE]/American Society of Reproductive Medicine [ASRM] consensus workshop group).

References:

Zawadski JK, Dunaif A. Diagnostic criteria for polycystic ovary syndrome: Towards a rational approach. In: Polycystic Ovary Syndrome (Current Issues in Endocrinology and Metabolism), Dunaif A, Givens JR, Haseltine FP, Merriam GE (Eds), Blackwell Scientific Inc, Boston 1992. p.377.
Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004; 19:41.
Azziz R, Carmina E, Dewailly D, et al. The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: The complete task force report. Fertil Steril 2009; 91:456.

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Proposed diagnostic criteria for polycystic ovary syndrome