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تعداد آیتم قابل مشاهده باقیمانده : 3 مورد
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Time to positivity of HIV diagnostic tests

Time to positivity of HIV diagnostic tests
Test Target of detection Approximate time to positivity (days)
Enzyme-linked immunoassay
First generation IgG antibody 35 to 45
Second generation IgG antibody 25 to 35
Third generation IgM and IgG antibody 20 to 30
Fourth generation IgM and IgG antibody and p24 antigen 15 to 20
Western blot
  IgM and IgG antibody 35 to 50 (indeterminate)
45 to 60 (positive)
HIV viral load test
Sensitivity cutoff 50 copies/mL RNA 10 to 15
Ultrasensitive cutoff 1 to 5 copies/mL RNA 5
This table demonstrates the approximate time to positivity following infection for various diagnostic tests for HIV.
IgG: immunoglobulin G; IgM: immunoglobulin M.
References:
  1. Branson BM, Stekler JD. Detection of acute HIV infection: We can't close the window. J Infect Dis 2012; 205:521.
  2. Owen SM. Testing for acute HIV infection: implications for treatment as prevention. Curr Opin HIV AIDS 2012; 7:125.
  3. Cohen MS, Gay CL, Busch MP, et al. The detection of acute HIV infection. J Infect Dis 2010; 202:S270.
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