Version June 2024
| Response type | International Union Against Cancer* | WHO¶ |
| Complete response | Disappearance of all known disease Lytic lesions should have radiologic evidence of calcification | Complete disappearance of all lesions on plain radiograph or scan for at least four weeks |
| Partial response | At least 50% decrease in size of measurable lesions Objective improvement in evaluable or nonmeasurable lesions No new lesions or progressive lesions | Partial decrease in size of lytic lesions, recalcification of lytic lesions, or decreased density of blastic lesions for at least four weeks |
| No change (stable disease) | Unchanged, or between 25% increase and 50% decrease in size of measurable lesionsΔ | Because of the slow response of bone lesions, the classification of "no change" should not be applied until at least eight weeks have passed from start of therapy |
| Progressive disease | Mixed; some lesions persist while others progress, or new lesions appear Failure; some or all lesions progress and/or new lesions appear No lesions regress | Increase in size of existent lesions or appearance of new lesions |
UICC: International Union Against Cancer; WHO: World Health Organization.
* Criteria are based on plain radiography; the duration of response is to be dated from the start of therapy until either new lesions appear or any one existing lesion increases by 25% or more above its smallest recorded size.
¶ Occurrence of bone compression or fracture and its healing should not be used as the sole indicator for evaluation of therapy.
Δ If lesions that cannot be measured but are otherwise evaluable represent the bulk of disease and these lesions clearly do not respond even though measurable lesions have improved, then the response is considered no change, rather than an objective regression.آیا می خواهید مدیلیب را به صفحه اصلی خود اضافه کنید؟
